Current perspectives on long-COVID: a brief review of understanding and management

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Paulina Martínez-Bretón
Brandon Colonna-Aguirre
Noé Zebadúa Rodríguez
María I. Iñiguez-Luna
Jorge D. Cadena-Zamudio

Keywords

SARS-CoV-2, COVID-19, Long-COVID, Viral infection, Sequelae

Resumen

Objective: Conduct a retrospective analysis of studies compiled in the literature on the current classification of Long-COVID.


Design/methodology/approach: A search was conducted in medical information platforms using the keywords: COVID-19, Long COVID, COVID.19 sequelae, SARS-CoV 2, prolonged COVID. Articles published in the chronological period between 2020 and 2023 in both English and Spanish were used. Inclusion criteria were a maximum of five years since publication, review articles, systematic reviews, meta-analyses or clinical practice guidelines. The exclusion criteria were that the articles exceeded the time limit, that they were opinion articles, case reports or trials.


Results: There is no homogenized definition or standardized guidelines or norms for the diagnosis of Long-COVID, the epidemiological studies are not completely corroborated and there is a great disparity between the incidence rates estimated in the different research works, same case for treatment.


Limitations on study/implications: The lack of homogeneity in the patterns of symptoms, classification and diagnosis by the literature and health officials.


Findings/conclusions: A multidisciplinary approach is required, where clinical findings, laboratory and imaging studies are integrated, to homogenize information in search of adequate and timely Long-COVID diagnoses and effective treatments for the benefit of patients.

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